Take a blood test for Alzheimer's in five hours
Inputtime：2018-11-14 15:07:00 Views：
Alzheimer's can be diagnosed by taking blood. Taiwan Normal University team pioneered the magnetic decrement immunoassay technology in the world, which can detect Alzheimer's disease through blood screening, with an accuracy of more than 85%. In addition to the detection time of only five hours, it is simpler and faster than the clinical examination of spinal fluid for about a week, and it can also diagnose the mild cognitive impairment in the previous stage of Alzheimer's disease.
The research team led by Hong zaoe, a chair professor of the Institute of optoelectronic technology of the Taiwan Normal University, and Qiu Mingzhang, a neurosurgeon of the Taiwan University Hospital, are engaged in brain and nerve research and develop the technology of serum screening for Alzheimer's disease. In addition to the technology transfer to the magnetic Biotechnology company, the technology was also published in the international journal "human brain mapping" last year.
The Institute of Optoelectronics and the Taida hospital are engaged in the research of brain and nerve. Through blood examination, Alzheimer's disease can be screened out, with an accuracy of at least 85%.
The research team said that when Alzheimer's disease and other brain neuropathy occur in the brain, a large number of index proteins of the disease will appear in cerebrospinal fluid, but the concentration is very low from the nervous system through the diffusion mechanism to the blood, so it is difficult to detect. At present, more spinal fluid is used for clinical examination.
However, spinal fluid collection is an invasive test, according to Hong, which is traditionally believed to cause injury and high risk. In addition, there are many biomarkers in spinal fluid, so it is not easy to detect Alzheimer's disease. When a plaque is seen in the brain of a patient, the brain nerve is usually damaged, and the patient is ill and hard to cure.
Hong said that the magnetic decrement immunoassay technology developed by the team has high sensitivity and specificity, which can be used to detect the extremely low concentration of target protein in the blood and detect Alzheimer's disease in advance. Since there is no radical cure method for the disease up to now, only drugs to slow down the symptoms are available. "Early detection of the symptoms can slow down the symptoms early.".
Qiu Mingzhang said that screening Alzheimer's disease with blood is more convenient for patients, and it may be helpful for long-term tracking and efficacy testing in the future. This technology has been used in Taida, Shuanghe, emcee, benevolence and other hospitals. It can be implemented in all hospitals in Taiwan as soon as next year. It will also be Ce (European certification) and FDA (US Food and Drug Administration) in the near future ）Etc.
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