[Significance of detection]
Congenital hypothyroidism is a neonatal endocrine disorder characterized by a decrease in the levels of thyroid hormones (T3 and T4) in the peripheral blood. The average incidence rate of congenital hypothyroidism is 1:4000 worldwide. This disease is characterized by a lower than normal level of thyroid hormone and a higher than normal level of thyrotropin (hTSH). Human thyrotropin is synthesized and secreted by the anterior pituitary gland. He regulates and stimulates the thyroid gland to produce thyroid hormones. Thyroxine deficiency stimulates the secretion of hTSH and has negative feedback. The level of hTSH is also affected by thyrotropin releasing hormone secreted by hypothalamus. Therefore, the increased concentration of thyrotropin in the peripheral blood of newborn can be used as the basis for screening and judging congenital hypothyroidism.
The deficiency of thyroid hormone in the period before and after birth and in the months after birth will hinder the normal development of the brain, and the final result is the irreparable brain dysfunction and the development of the skeletal nervous system. The congenital hypothyroidism of the newborn can be screened out in the early stage.
This kit is an in vitro assay kit for the quantitative determination of thyrotropin (hTSH) in dried blood samples on filter paper. To help detect neonatal congenital hypothyroidism
Enzyme linked immunosorbent assay
960 persons / box.
1. The operation process is detailed in the instruction;
2. Pass the verification of CCD;
3. The product background noise is very low;
4. High sensitivity and specificity;
5. It can be equipped with semi-automatic and full-automatic instruments;