Congenital heart disease is the most common birth defect, in China, for every 1,000 births, seven to eight of them are congenital heart disease patients, the incidence of which accounted for 0.4% to 1% of living infants, the number of sick babies born every year more than 200,000.

Australia zhang Ren Qian heart Institute (Victor ChangCardiac Research Institute) of Sally Dunwoodie professor's latest Research identified the NAD (also called coenzyme Ⅰ) abortion and as a result of the lack of a newborn in the heart, spine, kidneys, and the main reason for the problem of cleft palate, and clear the pregnant women VB3 (niacin) added to prevent the role of fetal congenital heart defects.

The study was published in The newEngland Journal of Medicine [1].

NAD coenzyme Ⅰ is a coenzyme, organism required in biological oxidation process plays the role of hydrogen transfer, can activate a variety of enzyme system, promote the synthesis of nucleic acid, protein, polysaccharide and metabolism, increase material transport and adjusting control, improve the metabolism.

Clinical can be used to treat coronary heart disease, to improve the symptoms of coronary heart disease such as chest distress, angina pectoris effective.

The study found that a lack of NAD synthesis during pregnancy impairs the formation of the embryo.

Vitamin B3 (niacin) is an important part of coenzyme Ⅰ, lack of VB3 can directly lead to the lack of coenzyme Ⅰ in the body.

But the study found that at least a third of the women in the first trimester consumed less vitamin B3, and 60 percent in the third trimester.

Previously, when folic acid was shown to work, mothers around the world voluntarily took folic acid supplements during pregnancy, resulting in a 70 percent reduction in neural tube defects.

Now professor Sally Dunwoodie's research means women should take vitamin B3 at an early age, even before they become pregnant, which could dramatically reduce miscarriage and birth defects around the world.

At present, there are few clinical methods for the detection of B vitamins, especially VB3 (nicotinic acid). The water-soluble vitamin detection kit (tandem mass spectrometry) developed by yingsheng biological institute can simultaneously detect nine kinds of vitamins necessary for human body, including VB1, VB2, VB3, VB5, VB6, VB7, VB7, VB9, VB12 and VC.

Only 2-3ml of peripheral blood (which can be carried out together with regular pregnancy examination) is needed to accurately monitor the levels of vitamins in the body at each stage of pregnancy and guide pregnant women to supplement vitamins reasonably and scientifically to ensure the health of the pregnant woman and the fetus.

Product details can be consulted at 400-609-9909

Literature reference


[1] Shi H, Enriquez A, Rapadas M,Martin EMMA. Wang R, Moreau J, Lim CK, Szot JO, Ip E, Hughes J, Sugimoto K,Humphreys D, McInerney-Leo AM, Leo PJ, Maghzal GJ, Halliday J, Smith J, ColleyA, Mark PR, Collins F, Sillence DO, Winlaw DS, Ho J, Guillemin GJ, Brown MA,Kikuchi K, Thomas PQ, Stocker R, Giannoulatou E, Chapman G, Duncan EL, SparrowDB, Dunwoodie SL. NAD Deficiency, Congenital Malformations and Niacin Supplementation. TheNew England Journal of Medicine. 2017; 377(6):544-552.